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MYP_157763
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Basic Information
Ocellatin-3N
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C89H152N22O26
Standard
Sequence
GIFDVLKNLAKGVITSLAS
Physicochemical Analysis
1946.29 Da
8.59
0.76
0.55
0.0400
0.91
0.69
0.34
2.56
143.68
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
780.24
-6.81
27.0
27.0
66.0
137.0
1.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0125907 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus nesiotus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
62.5 μM
MIC
PMID33092132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33092132/
RECORD: Rec_0161142 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus nesiotus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae ATCC 49472
62.5 μM
MIC
PMID33092132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33092132/
RECORD: Rec_0179153 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
PMID36426386 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/36426386/
RECORD: Rec_0180093 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus nesiotus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Mouse erythrocytes
98 μM
HC50
PMID33092132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33092132/
RECORD: Rec_0183996 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus nesiotus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923
12.5 μM
MIC
PaperPeptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad Spectrum Antimicrobial Activity
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