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MYP_157763
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Basic Information
Ocellatin-3N
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C89H152N22O26
Standard
Sequence
GIFDVLKNLAKGVITSLAS
Physicochemical Analysis
1946.29 Da
8.59
0.76
0.55
0.0400
0.91
0.69
0.34
2.56
143.68
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
780.24
-6.81
27.0
27.0
66.0
137.0
1.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001034 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus nesiotus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecium ATCC 19434
62.5 μM
MIC
PMID33092132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33092132/
RECORD: Rec_0003636 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus nesiotus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae ATCC BAA-2814
62.5 μM
MIC
PMID33092132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33092132/
RECORD: Rec_0008355 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus nesiotus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa ATCC 27853
25 μM
MIC
PaperPeptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad Spectrum Antimicrobial Activity
RECORD: Rec_0010120 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus nesiotus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Enterococcus faecalis ATCC 51299
250 μM
MIC
PaperPeptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad Spectrum Antimicrobial Activity
RECORD: Rec_0019292 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus nesiotus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 12600 or ATCC BAA-2312
31.25 μM
MIC
PaperPeptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad Spectrum Antimicrobial Activity
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