‹ ›
MYP_157744
← PREVIOUS NEXT → BACK
Basic Information
Defensin D7
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Plant bioactivity ▸ Plant defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
38 amino acids
C178H274N52O60S4
Standard
Sequence
GIFSSRKCKTPSKTFKGYCTRDSNCDTSCRYEGYPAGD
Physicochemical Analysis
4230.65 Da
8.83
2.72
2.45
0.0717
-1.06
0.59
-0.27
42.23
12.89
0.1316
4470.00
4720.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1847.27
-26.06
71.0
67.0
137.0
294.0
7.0
38.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0120706 VERIFIED: YES
Provenance & Taxonomy
Spinacia oleracea [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
R. solanacearum
1 μM
EC50
PMID9762899 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9762899/
RECORD: Rec_0122592 VERIFIED: YES
Provenance & Taxonomy
Spinacia oleracea [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0170249 VERIFIED: YES
Provenance & Taxonomy
Spinacia oleracea [Plant]
Defensin
3562
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Clavibacter michiganensis subsp. sepedonicus
0.1 μM
EC50
PaperPubMed PMID 9762899 PMID9762899 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9762899/
RECORD: Rec_0242099 VERIFIED: YES
Provenance & Taxonomy
Spinacia oleracea [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Fusarium spp
PaperPubMed PMID: 9762899 PMID9762899 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9762899/
RECORD: Rec_0245241 VERIFIED: YES
Provenance & Taxonomy
Spinacia oleracea [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
C. michiganensis
0.1 μM
EC50
PMID9762899 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9762899/
FIRST PREV 1 2 3 NEXT LAST
Showing 5 records on this page · Page 2 of 3