Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length550 amino acids

Chemical FormulaC2605H4066N792O800S20

DescriptionStandard

        MGYRSTNYGRGQALHGDRTTTGAICCSSLPNCTEHGRGVIRVGDKTTACPNCGKQGVVADGEPRVNWTGQASAVDGSVVICGCPHGTNRVIAPSGEWLGSGPSPEQIAHEKHQAMFAARRKEEEAEAQRQAEERDRNRVFAKSCLRGEGCNDVGTGSEPHTNFAEMAFSQAMPNDTPQHAQAAKRKPKQHGALYPGWNGHHEEMDYQAAAAAEERAWTARNAIADASELVLVGGRTVTPGTWAVRGAALGEIATGGPGAPAAGLLIGMFPGKLNDGEQDFIDRMRAEQMREAPTRVRFTWEYDANGKPTPRGWHTPPGKDSVRVRRMEWDSRRQAYTFTTEEDPGITLIWTPDRTGENKPWDTGNQNPVRIPNPVVVDPLPEDTRIGATTSPTPEEKTFADYILILPVGGVPPIYVFIRHNPGQVTGKGQKVSGVWLSDANAGNGSPIPSQIADRLRGQTFTDFDQFRKAFWMEVSRDPGLLEQFNRGNVGNIKAGKAPSPRENEQVGGKVKYEIHHIKPIVKGGEVYDIDNMGIVTPKRHIEIHRGGIN
    

Molecular Weight59920.28 Da

Isoelectric Point (pI)6.98

Net Charge (pH 7.0)-0.09

Net Charge (pH 7.4) -1.38

Charge Density (pH 7.0) -0.0002

GRAVY Index-0.67

Hydrophobic Moment 0.74

Boman Index-0.08

Instability Index35.00

Aliphatic Index 61.05

Aromaticity 0.0673

Extinction Coeff. Reduced 80900.00

Extinction Coeff. Oxidized 81400.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0259263 VERIFIED: YES

Provenance & Taxonomy

OrganismLelliottia amnigena [Animal]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)