Peptide Database

Peptide NameGlia-gamma30-gliadin (p222236; E225 and E231)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC70H115N19O24

DescriptionStandard

        VQGEGIIQPEQPAQL
    

Molecular Weight1606.77 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.26

Net Charge (pH 7.4) -2.47

Charge Density (pH 7.0) -0.1507

GRAVY Index-0.41

Hydrophobic Moment 0.31

Boman Index0.12

Instability Index61.59

Aliphatic Index 104.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 700.10

LogP -6.93

H-bond Donors 20.0

H-bond Acceptors 22.0

Rotatable Bonds 52.0

Heavy Atoms 113.0

Ring Count 2.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0411330 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E225; Reported substitutions/positions: E231

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman gluten-specific T cells / HLA-DQ2

MethodT-cell proliferation assay