Peptide Database

Peptide NameCorticotropin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC204H310N58O60S2

DescriptionStandard

        SYSMEHFRWGKPVGRKRRPVKVYPNGVEEESAEAYPTEM
    

Molecular Weight4599.13 Da

Isoelectric Point (pI)8.09

Net Charge (pH 7.0)0.56

Net Charge (pH 7.4) 0.28

Charge Density (pH 7.0) 0.0143

GRAVY Index-1.18

Hydrophobic Moment 0.68

Boman Index-0.24

Instability Index72.97

Aliphatic Index 34.87

Aromaticity 0.1282

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1912.59

LogP -17.45

H-bond Donors 67.0

H-bond Acceptors 64.0

Rotatable Bonds 147.0

Heavy Atoms 324.0

Ring Count 11.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0356383 VERIFIED: YES

Provenance & Taxonomy

OrganismLepisosteus osseus [Animal]

FamilyCorticotropin

Tax ID34771

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other Mods13:Valine amide

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0359730 VERIFIED: NO