Peptide Database

Peptide NameMaximins 3 H3 type 3 [Cleaved into: Maximin-3; Maximin-H3]

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Antiviral

Antiviral ▸ Anti-HIV

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Reproductive biology ▸ Contraceptive activity ▸ Spermicidal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC706H1164N202O217S3

DescriptionStandard

        MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRGIGGKILSGLKTALKGAAKELASTYLHRKRTAEEHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQDEIANLFTKKEKRILGPVLGLVGNALGGLIKKIG
    

Molecular Weight16050.21 Da

Isoelectric Point (pI)7.93

Net Charge (pH 7.0)0.71

Net Charge (pH 7.4) 0.34

Charge Density (pH 7.0) 0.0049

GRAVY Index-0.37

Hydrophobic Moment 0.67

Boman Index-0.08

Instability Index41.44

Aliphatic Index 98.26

Aromaticity 0.0556

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6850.32

LogP -66.58

H-bond Donors 240.0

H-bond Acceptors 223.0

Rotatable Bonds 565.0

Heavy Atoms 1128.0

Ring Count 12.0

Amide Bonds 152.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0312440 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyBombinin; Maximin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Antiviral Anti-HIV Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Cytotoxic Hemolytic Spermicidal

TargetGram Negative Bacteria and Gram Positive Bacteria

RECORD: Rec_0341263 VERIFIED: NO