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MYP_157519
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Basic Information
Magainin-C1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
23 amino acids
C110H180N30O30S
Standard
Sequence
GVGKFLHSAKKFGQALASEIMKS
Physicochemical Analysis
2434.85 Da
10.00
2.85
2.59
0.1237
-0.01
0.64
0.10
18.93
76.52
0.0870
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
977.36
-9.36
34.0
35.0
86.0
171.0
3.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011346 VERIFIED: YES
Provenance & Taxonomy
Xenopus clivii [Animal]
Magainin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
200.0 μM
HC50
PaperJ.M. Conlon et al. / Comparative Biochemistry and Physiology, Part C 153 (2011) 350-354. Purification and properties of antimicrobial peptides from skin secretions of the Eritrea clawed frog Xenopus clivii (Pipidae)
RECORD: Rec_0014228 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0018336 VERIFIED: YES
Provenance & Taxonomy
Xenopus clivii [Animal]
Magainin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
100.0 μM
MIC
PaperJ.M. Conlon et al. / Comparative Biochemistry and Physiology, Part C 153 (2011) 350-354. Purification and properties of antimicrobial peptides from skin secretions of the Eritrea clawed frog Xenopus clivii (Pipidae)
RECORD: Rec_0127315 VERIFIED: NO
Provenance & Taxonomy
Xenopus clivii [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0232785 VERIFIED: YES
Provenance & Taxonomy
Xenopus clivii [Animal]
Magainin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
100.0 μM
MIC
PaperJ.M. Conlon et al. / Comparative Biochemistry and Physiology, Part C 153 (2011) 350-354. Purification and properties of antimicrobial peptides from skin secretions of the Eritrea clawed frog Xenopus clivii (Pipidae)