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MYP_157504
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Basic Information
Callyaerin E
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
12 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
LPFFPPVXPIIG
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0047829 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
X=Daa
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 20599387 PMID20599387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20599387/
RECORD: Rec_0169852 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
X=Daa
Bio-Activity Profile
Antimicrobial Anticancer
HeLa
3.4 μM
ED50
PaperPubMed PMID: 20599387 PMID20599387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20599387/
RECORD: Rec_0173301 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
X=Daa
Bio-Activity Profile
Antimicrobial Anticancer
L5178Y
0.39 μM
ED50
PaperPubMed PMID: 20599387 PMID20599387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20599387/
RECORD: Rec_0227845 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
X=Daa
Bio-Activity Profile
Antimicrobial Anticancer
PC-12
3.8 μM
ED50
PaperPubMed PMID: 20599387 PMID20599387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20599387/
RECORD: Rec_0380627 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
X=Daa
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 20599387 PMID20599387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20599387/