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MYP_157451
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Basic Information
PST13-RK
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C97H136N22O14
Standard
Sequence
KKKFPWWWPFKKK
Physicochemical Analysis
1834.26 Da
10.70
5.75
5.54
0.4426
-1.82
0.14
-0.30
25.08
0.00
0.3846
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
598.43
2.66
21.0
20.0
57.0
133.0
10.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0095244 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
2 μg/mL
MIC
PMID16563706 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16563706/
RECORD: Rec_0098513 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli KCTC 1682
2 μg/mL
MIC
PaperDesign of perfectly symmetric Trp-rich peptides with potent and broad-spectrum antimicrobial activities.
RECORD: Rec_0106834 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0115392 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus subtilis KCTC 3068
2 μg/mL
MIC
PaperDesign of perfectly symmetric Trp-rich peptides with potent and broad-spectrum antimicrobial activities.
RECORD: Rec_0139019 VERIFIED: YES
Provenance & Taxonomy
Derivative of [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
NIH-3T3 (mouse)
83 μg/mL
IC50
PaperPubMed PMID: 18815734 PMID18815734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18815734/
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