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MYP_157405
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Basic Information
Arenicin-3 [Y5R;V6,15A], NZ17228
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C108H165N39O26S4
Standard
Sequence
GFCWRACVYRNGVRACYRRCN
Physicochemical Analysis
2553.97 Da
9.69
4.72
4.45
0.2247
-0.43
0.77
-0.29
65.36
37.14
0.1905
8480.00
8730.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1097.25
-11.64
46.0
35.0
79.0
177.0
5.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007845 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human embryonic kidney HEK293 cells (50% Cell death at >300 microg/ml
293 μg/mL
Hemolysis
PMID32576824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32576824/
RECORD: Rec_0122431 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20110306750A1/en PatentUS 2011/0306750 A1
RECORD: Rec_0155594 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Klebsiella pneumoniae BAA-2146
0.5 μg/mL
MIC
PMID32576824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32576824/
RECORD: Rec_0185206 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
0.125 μg/mL
MIC
PMID32576824 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32576824/
RECORD: Rec_0217132 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Arenicin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 25922
0.125 μg/mL
MIC
PaperAn amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria.
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