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MYP_157380
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Standard
4 amino acids
C23H37N7O6
Standard
Sequence
RYLG
Physicochemical Analysis
507.58 Da
8.75
0.76
0.55
0.1898
-0.60
0.84
-0.18
-11.35
97.50
0.2500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
232.75
-1.26
9.0
7.0
15.0
36.0
1.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0221721 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
224.69 μM
IC50
PaperResistance of casein-derived bioactive peptides to simulated gastrointestinal digestion | Contreras, M. del Mar. et al. | DOI: 10.1016/j.idairyj.2013.05.008 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0245026 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
Spontaneously hypertensive rats
PaperResistance of casein-derived bioactive peptides to simulated gastrointestinal digestion | Contreras, M. del Mar. et al. | DOI: 10.1016/j.idairyj.2013.05.008 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0349731 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperAmigo L., Mart¨ªnez-Maqueda D., Hern¨¢ndez-Ledesma B.. In silico and in vitro analysis of multifunctionality of animal food-derived peptides. Foods, 9, 991, 2020.
RECORD: Rec_0361183 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant Macrophage-modulating
Caco-2 cells
PaperIn Silico and In Vitro Analysis of Multifunctionality of Animal Food-Derived Peptides | Amigo, L. et al. | DOI: 10.3390/foods9080991 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0370411 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
225.0
IC50
PaperStuknyte M., Cattaneo S., Masotti F., De Noni I.. Occurrence and fate of ACE-inhibitor peptides in cheeses and in their digestates following in vitro static gastrointestinal digestion. Food Chemistry, 168, 27-33, 2015.