Peptide Database

Peptide NamePep27anal4

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC162H233N47O38S

DescriptionStandard

        MWKEFHNVLSSGQLLADKRWARWYNRW
    

Molecular Weight3478.94 Da

Isoelectric Point (pI)10.27

Net Charge (pH 7.0)2.59

Net Charge (pH 7.4) 2.32

Charge Density (pH 7.0) 0.0959

GRAVY Index-0.93

Hydrophobic Moment 0.77

Boman Index-0.15

Instability Index89.40

Aliphatic Index 61.48

Aromaticity 0.2222

Extinction Coeff. Reduced 23490.00

Extinction Coeff. Oxidized 23490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1414.06

LogP -8.34

H-bond Donors 52.0

H-bond Acceptors 43.0

Rotatable Bonds 111.0

Heavy Atoms 248.0

Ring Count 11.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0423282 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus pneumoniae [Bacterium]

FamilyS. pneumoniae

Tax ID1313

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Anticancer Cytotoxic

TargetJurkat

Activity46 μM

MethodIC50

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