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MYP_157358
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Basic Information
Pep27anal4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
27 amino acids
C162H233N47O38S
Standard
Sequence
MWKEFHNVLSSGQLLADKRWARWYNRW
Physicochemical Analysis
3478.94 Da
10.27
2.59
2.32
0.0959
-0.93
0.77
-0.15
89.40
61.48
0.2222
23490.00
23490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1414.06
-8.34
52.0
43.0
111.0
248.0
11.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0214267 VERIFIED: YES
Provenance & Taxonomy
Streptococcus pneumoniae [Bacterium]
S. pneumoniae
1313
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HL-60
51 μM
IC50
PMID16004618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16004618/
RECORD: Rec_0251824 VERIFIED: YES
Provenance & Taxonomy
Streptococcus pneumoniae [Bacterium]
Pep27 analog
1313.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
MCF-7
29.0 μM
IC50 / MTT-MTS assay
PaperPMID 16004618; Pep27anal4 cytotoxicity in breast cancer cells PMID16004618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16004618/
RECORD: Rec_0307329 VERIFIED: YES
Provenance & Taxonomy
S. pneumoniae [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 16004618 PMID16004618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16004618/
RECORD: Rec_0355492 VERIFIED: YES
Provenance & Taxonomy
S. pneumoniae [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
29 μM
IC50
PaperPubMed PMID: 16004618 PMID16004618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16004618/
RECORD: Rec_0398774 VERIFIED: YES
Provenance & Taxonomy
Streptococcus pneumoniae [Bacterium]
S. pneumoniae
1313
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
SNU-601
37 μM
IC50
PMID16004618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16004618/
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