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MYP_157356
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Basic Information
Hyastatin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
131 amino acids
C591H927N179O168S7
Standard
Sequence
MRVLLILVSLAALAHAESFLKSKTGYQGVQTLPGFIGGSQPHLGGGIGGGRPFISQPNLGGGIGGGIGGGKPFIPQPNLGGGIGSTRPFPRPQYGDYGSRNSCNRQCPSTYGGRGICCRRWGSCCPTNYKG
Physicochemical Analysis
13452.24 Da
9.99
10.61
10.19
0.0810
-0.25
0.49
0.09
55.36
66.26
0.0840
12950.00
13325.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
5471.45
-68.78
194.0
188.0
428.0
945.0
26.0
142.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0248704 VERIFIED: YES
Provenance & Taxonomy
Hyas araneus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Non-hemolytic
S. cerevisiae
PMID19487032 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19487032/
RECORD: Rec_0269431 VERIFIED: YES
Provenance & Taxonomy
Hyas araneus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Pseudomonas aeruginosa (Gram-negative)
PMID19487032 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19487032/
RECORD: Rec_0291801 VERIFIED: YES
Provenance & Taxonomy
Hyas araneus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
12.5 μM
MIC
PMID19487032 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19487032/
RECORD: Rec_0331415 VERIFIED: YES
Provenance & Taxonomy
Hyas araneus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
50 μM
MIC
PMID19487032 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19487032/
RECORD: Rec_0365541 VERIFIED: YES
Provenance & Taxonomy
Hyas araneus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Non-hemolytic
C. glutamicum (Gram-positive)
PMID19487032 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19487032/
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