Peptide Database

Peptide NameRelaxin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC178H289N55O51S2

DescriptionStandard

        TDDKKLKACGRDYVRLQIEVCGSIWWGRKAGQLRE
    

Molecular Weight4079.67 Da

Isoelectric Point (pI)9.23

Net Charge (pH 7.0)2.39

Net Charge (pH 7.4) 2.15

Charge Density (pH 7.0) 0.0682

GRAVY Index-0.77

Hydrophobic Moment 0.66

Boman Index-0.24

Instability Index39.40

Aliphatic Index 78.00

Aromaticity 0.0857

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1769.35

LogP -16.13

H-bond Donors 66.0

H-bond Acceptors 56.0

Rotatable Bonds 141.0

Heavy Atoms 286.0

Ring Count 5.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0118935 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

FamilyInsulin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0172728 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyRelaxin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 7.2 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0228429 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/