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MYP_157311
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
10 amino acids
C58H85N15O13
Standard
Sequence
VGINYWLAHK
Physicochemical Analysis
1200.39 Da
8.57
0.82
0.55
0.0819
0.11
0.04
0.30
9.18
117.00
0.2000
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
459.03
-1.20
16.0
15.0
36.0
86.0
4.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008019 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PMID10717843 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10717843/
RECORD: Rec_0048793 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-Lactalbumin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
327 μM
IC50
PaperAngiotensin I-converting enzyme inhibitory properties of whey protein digests: concentration and characterization of active peptides. | Pihlanto-Leppala, A. et al. | DOI: 10.1017/s0022029999003982 Evidence URLhttps://www.uniprot.org/uniprotkb/P00711/entry
RECORD: Rec_0065871 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
327 μM
IC50
PaperAngiotensin I-converting enzyme inhibitory properties of whey protein digests: concentration and characterization of active peptides. PMID10717843 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10717843/
RECORD: Rec_0110191 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-Lactalbumin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant DPPH radical scavenging
PaperFunction and characterization of novel antioxidant peptides by fermentation with a wild Lactobacillus plantarum 60. | Chen, L. et al. | DOI: 10.1016/j.lwt.2020.110162 Evidence URLhttps://www.uniprot.org/uniprotkb/P00711/entry
RECORD: Rec_0154867 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 50.0%, C 50.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
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