Peptide Database

Peptide NamePeptide 144

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC103H169N35O23

DescriptionStandard

        RPDKPRPLSPFPRPPRPVR
    

Molecular Weight2265.66 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.56

Charge Density (pH 7.0) 0.2505

GRAVY Index-1.72

Hydrophobic Moment 0.77

Boman Index-0.58

Instability Index89.38

Aliphatic Index 35.79

Aromaticity 0.0526

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 909.85

LogP -7.97

H-bond Donors 30.0

H-bond Acceptors 28.0

Rotatable Bonds 61.0

Heavy Atoms 161.0

Ring Count 9.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0111895 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-Term1-Amino cyclohexyl carboxylic acid

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli BW25113

Activity128 μg/mL

MethodMIC

RECORD: Rec_0397025 VERIFIED: YES