Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length212 amino acids

Chemical FormulaC1027H1656N260O298S13

DescriptionStandard

        GISEFTLNSASFGYFSAGELQAFINDSMIPPCIPFHLNTSSMGMFIPQLPKMYPGLLMNLQVNAKQAPMFSLQLGSGLLDVQVDVKAAAIEANGTQIPLFTLSVNSSFTGKMMIADGKLKGNVMLNNVTLTVEATEIGEFKTDALKSGIKSGMIVALGQLNAKLGKGIILPRMKHAQLVNTILKMQKGFVAIYSDVQILQTDRSSFLSTSYL
    

Molecular Weight22830.54 Da

Isoelectric Point (pI)8.97

Net Charge (pH 7.0)2.93

Net Charge (pH 7.4) 2.57

Charge Density (pH 7.0) 0.0138

GRAVY Index0.28

Hydrophobic Moment 0.56

Boman Index0.21

Instability Index26.10

Aliphatic Index 101.23

Aromaticity 0.0755

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0297098 VERIFIED: NO

Provenance & Taxonomy

OrganismPoeciliopsis prolifica [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria