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MYP_157253
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Basic Information
Os
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
22 amino acids
C109H171N31O28S3
Standard
Sequence
KGIRGYKGGYCKGAFKQTCKCY
Physicochemical Analysis
2459.91 Da
9.67
5.72
5.46
0.2601
-0.80
0.45
-0.17
-11.80
22.27
0.1818
4470.00
4595.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
990.43
-9.77
39.0
37.0
84.0
171.0
4.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011110 VERIFIED: YES
Provenance & Taxonomy
Ornithodoros savignyi [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus
PMID31713951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31713951/
RECORD: Rec_0011775 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0040882 VERIFIED: YES
Provenance & Taxonomy
Ornithodoros savignyi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
0.77 μM
MIC
RECORD: Rec_0043559 VERIFIED: YES
Provenance & Taxonomy
Ornithodoros savignyi [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa
PMID31713951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31713951/
RECORD: Rec_0055033 VERIFIED: YES
Provenance & Taxonomy
Ornithodoros savignyi [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
0.76 μM
MBC
PMID26662999 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26662999/
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