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MYP_157244
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Basic Information
CP10A (Indolicidin peptide derivative; mammals, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C94H125N25O14
Standard
Sequence
ILAWKWAWWAWRR
Physicochemical Analysis
1829.16 Da
12.00
2.76
2.55
0.2122
-0.28
0.55
0.14
44.98
83.08
0.3846
27500.00
27500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
641.29
2.64
26.0
17.0
51.0
133.0
10.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0196429 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 61.5%, E 0.0%, T 7.7%, C 30.8% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0223802 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Listeria monocytogenes
PMID11294848 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11294848/
RECORD: Rec_0276299 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus hemolyticus
PMID11294848 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11294848/
RECORD: Rec_0285180 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Rat erythrocytes
5 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/8849687/ PMID8849687 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8849687/
RECORD: Rec_0291659 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus epidermidis Clinical isolate
2 μg/mL
MIC
PMID11294848 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11294848/
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