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MYP_157153
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Basic Information
M2 NH
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-H1N1
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C84H143N31O21S
Standard
Sequence
RLAAKCAARFAEHGLKRG
Physicochemical Analysis
1955.29 Da
10.92
3.84
3.57
0.2132
-0.38
0.69
-0.23
8.17
71.11
0.0556
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
861.74
-8.85
33.0
27.0
67.0
137.0
2.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0155066 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-H1N1
H1N1
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperEnvelope-deforming antiviral peptide derived from influenza virus M2 protein. | Jung Y, Kong B, Moon S, Yu SH, Chung J, Ban C, Chung WJ, Kim SG, Kweon DH. | Biochem Biophys Res Commun. 2019 Sep 24;517(3):507-512. | DOI:10.1016/j.bbrc.2019.07.088 | PMID:31375212 PMID31375212 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31375212/
RECORD: Rec_0292688 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PMID31375212 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31375212/
RECORD: Rec_0297254 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
H1N1:did not exhibit any inhibitory effect
PMID31375212 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31375212/