Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length565 amino acids

Chemical FormulaC2720H4307N815O837S20

DescriptionStandard

        MGYRTDNFGRGQALENDKTTTGARCIASITDSTEFGRRILRVGDKTTPCPKCGRKGVIVSGEERVTFHGVPVAVHGSKVHCDCPPGSNRVIAPAGQWLGRGRDPVDVAREQHAARLAAEKQAEENRREEERERNRVFAKSCLRGDGCNDAGDEREPHTNFADMAFFLAMPASDPATDSDTPQHAQTARKKKPEDIPRPKKRSALYRWWNGNQEEMDYQAAVAAATAATRAQTATAGASLLELISGRALTYGTWAVRGAAGLGEIAAAGAGAPVAGLLVGMMPGRLNDGEQDFIDRMRLAQMREAPSRVRYTWESNSRGNPVPHGWHTPPGRDSVRVRKMEYDSSAQAYTFTTEEEPRITIVWTPDRTDEKKPWNTGDQARPVLPNPVVVDPLPVNTGITATTSPAQEEKRFADYILILPFPDLPPIYIYLSKPPVEFLEVELYSDFKRRSRQGMYEADHMPSRAAVDAYLRANYPLLDDDEILALTDKVAAIVIPKDMHHKISETYGGRNTPTQIDLDSRNLRAAVDRNLDAIKPALKDHGATEIQIEAARVKMHKINSEAGLYK
    

Molecular Weight62458.56 Da

Isoelectric Point (pI)6.91

Net Charge (pH 7.0)-0.33

Net Charge (pH 7.4) -1.46

Charge Density (pH 7.0) -0.0006

GRAVY Index-0.62

Hydrophobic Moment 0.95

Boman Index-0.12

Instability Index44.96

Aliphatic Index 69.52

Aromaticity 0.0655

Extinction Coeff. Reduced 67840.00

Extinction Coeff. Oxidized 68215.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0100590 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacter cloacae [Bacterium]

FamilyPyocin/Colicin

Tax ID550

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli