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MYP_157090
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Basic Information
Cathelicidin-AL
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
48 amino acids
C171H296N86O56
Standard
Sequence
RRSRRGRGGGRRGGSGGRGGRGGGGRSGAGSSIAGVGSRGGGGGRHYA
Physicochemical Analysis
4452.72 Da
12.00
11.85
11.59
0.2468
-1.22
0.69
-0.34
110.74
20.42
0.0208
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2344.11
-45.51
93.0
69.0
156.0
313.0
2.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000397 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Cathelicidin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
5.6 μM
MIC
PaperX. Hao et al. / Amino Acids (2011) DOI 10.1007/s00726-011-1116-7. Amphibian cathelicidin fills the evolutionary gap of cathelicidin in vertebrate
RECORD: Rec_0015114 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Psecdomonas aeruginosa PA01
12.5 μg/mL
MIC
PMID22009138 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22009138/
RECORD: Rec_0025492 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0038832 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus subtilis
100 μg/mL
MIC
PMID22009138 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22009138/
RECORD: Rec_0051971 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC 43300
6.25 μg/mL
MIC
PaperAmphibian cathelicidin fills the evolutionary gap of cathelicidin in vertebrate.
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