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MYP_157072
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Basic Information
Phylloseptin-PBa (frog, amphibians, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
20 amino acids
C97H159N23O24S
Standard
Sequence
FFSMIPKIAGGIASLVKNLG
Physicochemical Analysis
2063.50 Da
10.00
1.76
1.55
0.0879
1.03
0.54
0.45
4.30
122.00
0.1000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
743.02
-4.71
25.0
27.0
68.0
145.0
3.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0040989 VERIFIED: YES
Provenance & Taxonomy
the Peruvian Purple-Sided Leaf Frog,Phyllomedusa baltea,South America [Animal]
Phylloseptin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus
8 μg/mL
MIC
PMID26633506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26633506/
RECORD: Rec_0111499 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa baltea [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
8
MIC
PMID26633506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26633506/
RECORD: Rec_0131209 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa baltea [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
128 μg/mL
MIC
PMID26633506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26633506/
RECORD: Rec_0169211 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa baltea [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Horse blood cells
256 μg/mL
Hemolysis
PMID26633506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26633506/
RECORD: Rec_0179221 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa baltea [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Staphylococcus aureus
8 μg/mL
MIC
PaperPhylloseptin-PBa--A Novel Broad-Spectrum Antimicrobial Peptide from the Skin Secretion of the Peruvian Purple-Sided Leaf Frog (Phyllomedusa Baltea) Which Exhibits Cancer Cell Cytotoxicity.
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