Peptide Database

Peptide NameNPWGQ

Function Ontology

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC27H36N8O8

DescriptionStandard

        NPWGQ
    

Molecular Weight600.62 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0480

GRAVY Index-1.98

Hydrophobic Moment 0.45

Boman Index-0.04

Instability Index-24.26

Aliphatic Index 0.00

Aromaticity 0.2000

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 272.90

LogP -2.66

H-bond Donors 8.0

H-bond Acceptors 8.0

Rotatable Bonds 15.0

Heavy Atoms 43.0

Ring Count 3.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0316785 VERIFIED: YES

Provenance & Taxonomy

OrganismHolothuroidea [Animal]

Familysea cucumber gonad-derived peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antioxidant SOD activation

TargetABTS at 5 mg/mL; DPPH; SOD

Activity98.9 ± 0.34 %

MethodABTS assay; DPPH radical scavenging assay; SOD activation assay