Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC405H634N110O134S12

DescriptionStandard

        MKTFAVAVTVSLLLTFLCVQENSAVPADELRGLEVPTDDGSRTADQETPEESWNMPYDMRENNYPGPVRCRFCCGCCLADVCGLCCD
    

Molecular Weight9572.80 Da

Isoelectric Point (pI)4.21

Net Charge (pH 7.0)-8.56

Net Charge (pH 7.4) -8.93

Charge Density (pH 7.0) -0.0984

GRAVY Index-0.09

Hydrophobic Moment 0.53

Boman Index0.02

Instability Index46.81

Aliphatic Index 69.43

Aromaticity 0.0690

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3887.99

LogP -42.89

H-bond Donors 140.0

H-bond Acceptors 138.0

Rotatable Bonds 304.0

Heavy Atoms 661.0

Ring Count 13.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0342527 VERIFIED: NO

Provenance & Taxonomy

OrganismPoecilia reticulata [Bacterium]

FamilyHepcidin family

Tax ID8081

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic

MethodQualitative functional evidence