Peptide Database

Peptide NameCycloviolacin H4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC135H221N35O41S6

DescriptionStandard

        GIPCGESCVYIPCTVTALLGCSCRDKVCYK
    

Molecular Weight3182.80 Da

Isoelectric Point (pI)7.76

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.40

Charge Density (pH 7.0) 0.0234

GRAVY Index0.56

Hydrophobic Moment 0.34

Boman Index0.17

Instability Index22.88

Aliphatic Index 84.33

Aromaticity 0.0667

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1199.56

LogP -12.38

H-bond Donors 48.0

H-bond Acceptors 48.0

Rotatable Bonds 99.0

Heavy Atoms 217.0

Ring Count 4.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0203796 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)