Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length539 amino acids

Chemical FormulaC2505H3982N682O774S11

DescriptionStandard

        PETVPVHSRIQDDVHDGAQFISVTGSGSQPYNLPVIKATPTPRGPYYTIGHLPGPMGPYTFTFNANAPHSEMHFARDEEKVSALHPAGFTVGANTTDCIVVFPEGSGLEPLYFSMTVILPEGPLKQRQEEENQARAKADAEAKAKAEAEAKAKAEAEAKAKAEREALFARAGVVPAPTYTPEMVKSAEAALGAAGVMVLGQTPGAMQLSVAGGGVLTATGEILSSLGAAVGRVIASLGATATAGTAGPMVAAASAILFSPAAGGGSDRVPGRDLNAMFALNAQLLAGPDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPPPAAPSDTASPPPSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGVEPVYVMLNDPLDSGRFTRKQLDKKYLKHASDFGIDDTKKNRETLTKFRDVIEAHLIDKETIKKGTYLPEKDSEVFFNSKTNNVVILNKDGNFVSGWKLTPGTPQYDVYTKTGNLK
    

Molecular Weight56389.23 Da

Isoelectric Point (pI)5.68

Net Charge (pH 7.0)-8.10

Net Charge (pH 7.4) -8.82

Charge Density (pH 7.0) -0.0150

GRAVY Index-0.17

Hydrophobic Moment 0.77

Boman Index0.08

Instability Index33.47

Aliphatic Index 81.17

Aromaticity 0.0575

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 28880.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0036281 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin/Colicin

Tax ID28901

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli