Peptide Database

Peptide NameSLAY-screened peptide P3051

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC75H130N22O23S2

DescriptionStandard

        TYNCSTLRSIRMTLI
    

Molecular Weight1772.10 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)1.39

Net Charge (pH 7.4) 1.18

Charge Density (pH 7.0) 0.0925

GRAVY Index0.23

Hydrophobic Moment 0.46

Boman Index-0.02

Instability Index47.63

Aliphatic Index 104.00

Aromaticity 0.0667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 758.99

LogP -8.47

H-bond Donors 30.0

H-bond Acceptors 27.0

Rotatable Bonds 58.0

Heavy Atoms 122.0

Ring Count 1.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0062872 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/