Peptide Database

Peptide NameHepcidin

Function Ontology

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Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC86H144N26O25S8

DescriptionStandard

        ICTLCCGCCNKQKCGWCCKT
    

Molecular Weight2198.74 Da

Isoelectric Point (pI)8.52

Net Charge (pH 7.0)2.68

Net Charge (pH 7.4) 2.35

Charge Density (pH 7.0) 0.1339

GRAVY Index0.33

Hydrophobic Moment 0.25

Boman Index0.01

Instability Index55.63

Aliphatic Index 39.00

Aromaticity 0.0500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 836.71

LogP -10.58

H-bond Donors 37.0

H-bond Acceptors 36.0

Rotatable Bonds 72.0

Heavy Atoms 145.0

Ring Count 2.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0356955 VERIFIED: YES

Provenance & Taxonomy

OrganismEquus asinus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)