Peptide Database

Peptide NameGnRH

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Reproductive neuropeptide

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC55H76N16O15

DescriptionStandard

        EHWSYGLRPG
    

Molecular Weight1201.29 Da

Isoelectric Point (pI)6.85

Net Charge (pH 7.0)-0.08

Net Charge (pH 7.4) -0.30

Charge Density (pH 7.0) -0.0077

GRAVY Index-1.28

Hydrophobic Moment 0.51

Boman Index-0.06

Instability Index28.61

Aliphatic Index 39.00

Aromaticity 0.2000

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 500.56

LogP -3.66

H-bond Donors 18.0

H-bond Acceptors 16.0

Rotatable Bonds 34.0

Heavy Atoms 86.0

Ring Count 5.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046757 VERIFIED: YES

Provenance & Taxonomy

OrganismBranchiostoma lanceolatum [Animal]

FamilyGnRH

Tax ID7740

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0085089 VERIFIED: NO

Provenance & Taxonomy

OrganismBranchiostoma lanceolatum [Animal]

FamilyGnRH

Tax ID7740

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Hormone Reproductive neuropeptide

RECORD: Rec_0330103 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/