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MYP_156920
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Basic Information
SPKQDFMRF-amide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Standard
9 amino acids
C52H78N14O14S
Standard
Sequence
SPKQDFMRF
Physicochemical Analysis
1155.33 Da
8.46
0.46
0.25
0.0511
-1.14
0.50
-0.31
88.62
0.00
0.2222
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
475.87
-3.85
16.0
16.0
37.0
81.0
3.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0036077 VERIFIED: NO
Provenance & Taxonomy
Drosophila melanogaster [Animal]
SPKQDFMRF-amide
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Neuromodulator Myotropic Receptor modulation
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0040049 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
FMRFamide related peptide
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
RFamide Neuropeptide Neuromodulator
PMID20869420 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20869420/
RECORD: Rec_0055637 VERIFIED: YES
Provenance & Taxonomy
Delia radicum [Animal]
FMRFamide related peptide
30064
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
RFamide Neuropeptide Neuromodulator
PMID20869420 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20869420/
RECORD: Rec_0074083 VERIFIED: YES
Provenance & Taxonomy
Drosophila virilis [Animal]
FMRFamide related peptide
7244
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
RFamide Neuropeptide Neuromodulator
PMID20869420 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20869420/
RECORD: Rec_0095368 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
FMRFamide-like peptide
7227.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Cardioactive Neuromodulatory
Drosophila melanogaster heart
Cardiac contractility assay
PaperPMID 24069424. Drosophila FMRFamide peptides (including SPKQDFMRFamide) modulate cardiac contractility via FMRFa-R. PMID24069424 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24069424/
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