Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length169 amino acids

Chemical FormulaC817H1305N233O235S9

DescriptionStandard

        MNPSTVKRCLVGAVLAIAATLPGFQQLHTSVEGLKLIADYEGCRLQPYQCDAGVWTDGIGNTSGVVPGKTITERQAAGSFITNVLRVEKALDRCVLVSVPQNVYDALVSLAFNVGTGNACGSTMVKFINQKRWREACYQLPRWVYVKGVFNTGLDNRRARELSWCLKGA
    

Molecular Weight18440.11 Da

Isoelectric Point (pI)9.19

Net Charge (pH 7.0)6.53

Net Charge (pH 7.4) 6.13

Charge Density (pH 7.0) 0.0386

GRAVY Index0.03

Hydrophobic Moment 0.72

Boman Index0.07

Instability Index31.93

Aliphatic Index 92.25

Aromaticity 0.0828

Extinction Coeff. Reduced 29450.00

Extinction Coeff. Oxidized 29825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7545.93

LogP -77.31

H-bond Donors 270.0

H-bond Acceptors 252.0

Rotatable Bonds 604.0

Heavy Atoms 1294.0

Ring Count 25.0

Amide Bonds 185.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008159 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage ST15-OXA48phi14.1 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic

RECORD: Rec_0271246 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyLysozyme

Tax ID573

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence