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MYP_156855
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Basic Information
LP25
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Protein Prenyltransferases Inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxin
not Standard
5 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XXXXX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0058415 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
residue-level stereochemical modification [Mixed]
None
Amidation
Gla=Carboxyglutamic acid
Bio-Activity Profile
Antiparasitic Antimicrobial Antiplasmodial Protein Prenyltransferases Inhibitor
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
RECORD: Rec_0059885 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Octadecanoic acid (C18)
ornithine at 1,2,3,4,5
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PA01
PMID30588791 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30588791/
RECORD: Rec_0060225 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)12CO
Amidation
Ornithine at 1,2,3,4,5; Ornithine
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa MTCC 2295
6.25 μg/mL
PMID23819506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23819506/
RECORD: Rec_0061130 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)10CO
Amidation
Ornithine at 1,2,3,4,5; Ornithine
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Aspergillus fumigatus ATCC 42203
12.5 μg/mL
PMID23819506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23819506/
RECORD: Rec_0065833 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Octadecanoic acid (C18)
ornithine at 1,2,3,4,5
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Cryptococcus neoformans var. grubii H99 ATCC 20882
0.25 μg/mL
MIC
PMID30588791 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30588791/
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