Peptide Database

Peptide NameSakacin P/ Sakacin 674

Function Ontology

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Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC98H142N28O25S2

DescriptionStandard

        KYYGNGVYCGKHKCRVDW
    

Molecular Weight2176.48 Da

Isoelectric Point (pI)9.19

Net Charge (pH 7.0)2.82

Net Charge (pH 7.4) 2.53

Charge Density (pH 7.0) 0.1568

GRAVY Index-1.06

Hydrophobic Moment 0.34

Boman Index-0.19

Instability Index-5.58

Aliphatic Index 32.22

Aromaticity 0.2222

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 883.53

LogP -6.76

H-bond Donors 34.0

H-bond Acceptors 31.0

Rotatable Bonds 69.0

Heavy Atoms 153.0

Ring Count 6.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0357832 VERIFIED: YES

Provenance & Taxonomy

OrganismLactobacillus ruminis [Bacterium]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)