Peptide Database

Peptide NameType VI secretion system effector; Hcp1 family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length596 amino acids

Chemical FormulaC2978H4583N791O873S15

DescriptionStandard

        MGDIVYLRIIGEKQGDISSGCGTYASVGNRWQVGHEDEIFAFALTNAITSTGKGVNLQGLQFCKLIDKSSPLLSNAINQNERLFIEIDLYRINKSGRWERYYYIQLRNASLTAIHVNISDNNLPTECVTVDYDYILCKHLIANTEFDWLAFPAGYNSLFIPPKSPPASNLKPEPLPVVNLPLSSPAVNPVYAKSCLKEKGCTDAGTAEEPAENFGQVAIFAQPVVDDCCGYHHPEANVIGEPAEAQTMLLFPGRVLAAQIWGKWSLSGILSATRGSYIGALASALYIPSAGEGSARVPGRDEFWYEEELRQKALAGSTATTRVRFFWGTDIHGKPQVYGVHTGEGTPYENVRVANMQWNEQTQRYEFTPAHDVDGPLITWTPENPEHGNVPGHTGNDRPPLDQPTILVTPIPDGTDTYTTPPFPVPDPKEFNDYILVFPAGSGIKPIYVYLKEDPRKLPGVVTGRGVPLSPGTRWLGMSVSNNGNGAPIPAHIADKLRGREFKTFDEFREALWLEVSQDPELIAQFSSGNQTRIKQGLTQKHHLKVGIMALKKSLKNSRYIIVLQLNMAAAYTILIIYELLPPDYTMRFTTGDKYV
    

Molecular Weight65915.00 Da

Isoelectric Point (pI)5.78

Net Charge (pH 7.0)-9.37

Net Charge (pH 7.4) -10.52

Charge Density (pH 7.0) -0.0157

GRAVY Index-0.28

Hydrophobic Moment 0.56

Boman Index0.07

Instability Index34.49

Aliphatic Index 84.45

Aromaticity 0.0990

Extinction Coeff. Reduced 99240.00

Extinction Coeff. Oxidized 99740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0157573 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli