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MYP_156679
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Standard
84 amino acids
C342H532N98O118S
Standard
Sequence
GETDPNTQLLNDLGNNMAWGAALGAPGGLGSAALGAAGGALQTVGQGLIDHGPVNVFIPVLIGPSWNGSGSGYNSATSSSGSGS
Physicochemical Analysis
7936.53 Da
4.05
-4.15
-4.41
-0.0494
0.07
0.52
0.28
18.91
81.43
0.0476
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3378.48
-50.44
112.0
116.0
249.0
559.0
12.0
93.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0189936 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0197774 VERIFIED: YES
Provenance & Taxonomy
Klebsiella pneumoniae [Bacterium]
Bacteriocin
573
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Attachment to a siderophore ester
The post-translational modification consists of a trimer of N-(2,3-dihydroxybnenzoyl)-L-serine linked via a C-glycosidic linkage to a β-D-glucose moiety, itself linked to the MccE492m Ser-84-carboxyl through an O-glycosidic bond
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli W3110
0.02 μM
MIC
PMID12890026;15102848;7682973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12890026/
RECORD: Rec_0197918 VERIFIED: YES
Provenance & Taxonomy
Klebsiella pneumoniae [Bacterium]
Bacteriocin
573
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Attachment to a siderophore ester
The post-translational modification consists of a trimer of N-(2,3-dihydroxybnenzoyl)-L-serine linked via a C-glycosidic linkage to a β-D-glucose moiety, itself linked to the MccE492m Ser-84-carboxyl through an O-glycosidic bond
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli GM1
0.04 μM
MIC
PMID12890026;15102848;7682973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12890026/
RECORD: Rec_0199509 VERIFIED: YES
Provenance & Taxonomy
Klebsiella pneumoniae [Bacterium]
Bacteriocin
573
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Attachment to a siderophore ester
The post-translational modification consists of a trimer of N-(2,3-dihydroxybnenzoyl)-L-serine linked via a C-glycosidic linkage to a β-D-glucose moiety, itself linked to the MccE492m Ser-84-carboxyl through an O-glycosidic bond
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli ML35p
0.14 μM
MIC
PMID12890026;15102848;7682973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12890026/
RECORD: Rec_0250508 VERIFIED: YES
Provenance & Taxonomy
Klebsiella pneumoniae [Bacterium]
Bacteriocin
573
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Attachment to a siderophore ester
The post-translational modification consists of a trimer of N-(2,3-dihydroxybnenzoyl)-L-serine linked via a C-glycosidic linkage to a β-D-glucose moiety, itself linked to the MccE492m Ser-84-carboxyl through an O-glycosidic bond
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli C600 pHX405
0.16 μM
MIC
PMID12890026;15102848;7682973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12890026/
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