Peptide Database

Peptide NamePeptide 8

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC109H170N36O26S2

DescriptionStandard

        KKHRCRVYNNGLPTGLYRWC
    

Molecular Weight2464.87 Da

Isoelectric Point (pI)10.06

Net Charge (pH 7.0)4.82

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.2412

GRAVY Index-1.06

Hydrophobic Moment 0.48

Boman Index-0.32

Instability Index23.79

Aliphatic Index 53.50

Aromaticity 0.1500

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1036.51

LogP -9.25

H-bond Donors 40.0

H-bond Acceptors 34.0

Rotatable Bonds 78.0

Heavy Atoms 173.0

Ring Count 6.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0086978 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus ATCC 6538

Activity2.4 μM

MethodMIC