Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length473 amino acids

Chemical FormulaC2284H3640N596O659S17

DescriptionStandard

        MLPAVIVGLMLVSLTCGENPAVQVILTNKGLQYGKHVGAGWIQEKLESVTFPDISGKLRIGILGNVHYTLTGARITKCDFPEPSVEFYQSATGFKTSVSGLSVALTGEWRAHYGPIHSGGTFNMAVFNVAVTSVVKLGNDTNRHLSVSSVHCDAGVGGVNIQFHGGSSWIIEKVVDHYKGRIAGDIRDGICPKVQESIAILEQHLQAMNVSFNVNQVVTLDLPLTGLPVVDASSLNLGLKGEFYSIKAPAEPPFQAKPFTVPEQPGRMLSVGLSEFTLNSASFGYFSAGVLQAVINDSMIPKFSPVHLNTSSMGPYVPQLPKMFPGLLVSLQVYAREVPLFSFLPGAVCLDLKGAVKAFAIQPNGTQTPLFKLNVDSLFSGKVWIADGRLKGSMKLNNLTVTLVSSEVGTVKTDAIQNILLKVSSIAMAKVNQILGKGVSLPRMKQAELVNTVLELDKGFIAVSSDAQVLMSD
    

Molecular Weight50538.03 Da

Isoelectric Point (pI)8.45

Net Charge (pH 7.0)3.36

Net Charge (pH 7.4) 2.47

Charge Density (pH 7.0) 0.0071

GRAVY Index0.24

Hydrophobic Moment 0.62

Boman Index0.19

Instability Index32.96

Aliphatic Index 102.75

Aromaticity 0.0740

Extinction Coeff. Reduced 35410.00

Extinction Coeff. Oxidized 35660.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0218813 VERIFIED: NO

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria