Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length101 amino acids

Chemical FormulaC508H803N139O152S8

DescriptionStandard

        VPVMKPYLMTISILLILVHKTPGGLFRSSYGKKQEEPWNPCQLYHGTCRNACRKHEILYLTCLDDQKCCLKFSKKIANANEKEDSDSDSNSFTNPSSYSRI
    

Molecular Weight11546.17 Da

Isoelectric Point (pI)8.77

Net Charge (pH 7.0)3.94

Net Charge (pH 7.4) 3.46

Charge Density (pH 7.0) 0.0390

GRAVY Index-0.53

Hydrophobic Moment 0.60

Boman Index-0.09

Instability Index55.63

Aliphatic Index 73.37

Aromaticity 0.0891

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4715.85

LogP -48.71

H-bond Donors 168.0

H-bond Acceptors 167.0

Rotatable Bonds 384.0

Heavy Atoms 807.0

Ring Count 19.0

Amide Bonds 109.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0246136 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence