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MYP_156575
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Basic Information
Brevinin-20b
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
33 amino acids
C152H253N43O42S2
Standard
Sequence
GIFNVFKGALKTAGKHVAGSLLNQLKCKVSGEC
Physicochemical Analysis
3419.03 Da
9.60
3.83
3.53
0.1159
0.22
0.60
0.14
-4.12
94.55
0.0606
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1380.56
-14.47
49.0
49.0
119.0
239.0
3.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0193734 VERIFIED: YES
Provenance & Taxonomy
Rana ornativentris [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
9 μM
MIC
PMID11892844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11892844/
RECORD: Rec_0229169 VERIFIED: YES
Provenance & Taxonomy
Rana Ornativentris [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus
PaperPubMed PMID: 11892844 PMID11892844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11892844/
RECORD: Rec_0240575 VERIFIED: YES
Provenance & Taxonomy
Montane brown [Animal]
Brevinin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial
PMID11892844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11892844/
RECORD: Rec_0258754 VERIFIED: YES
Provenance & Taxonomy
Rana ornativentris [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
4 μM
MIC
PMID11892844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11892844/
RECORD: Rec_0266545 VERIFIED: YES
Provenance & Taxonomy
Rana ornativentris [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
27-33
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
4.0 μM
MIC
PaperJ.B. Kim et al. / The Journal of Peptide Research 58 (2008) 349-356. Antimicrobial peptides from the skin of the Japanese mountain brown frog, Rana ornativentris
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