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MYP_156518
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Basic Information
Oxyopinin 2b
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Insecticidal/Pest control ▸ Insecticidal activity
Standard
37 amino acids
C189H305N51O49
Standard
Sequence
GKFSGFAKILKSIAKFFKGVGKVRKGFKEASDLDKNQ
Physicochemical Analysis
4075.76 Da
10.30
6.76
6.54
0.1826
-0.46
0.87
-0.09
-15.88
65.95
0.1351
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1665.77
-14.87
58.0
56.0
148.0
289.0
5.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0096170 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0105582 VERIFIED: YES
Provenance & Taxonomy
Oxyopes kitabensis [Animal]
Oxyopinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperJ Biol Chem. 2002 Jun 28;277(26):23627-37. Epub 2002 Apr 25. | http://www.ncbi.nlm.nih.gov/pubmed/11976325 PMID11976325 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11976325/
RECORD: Rec_0159492 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 94.6%, E 0.0%, T 0.0%, C 5.4% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0193587 VERIFIED: YES
Provenance & Taxonomy
Oxyopes kitabensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Insecticidal
Escherichia coli
12.5 μM
MIC
PaperOxyopinins, large amphipathic peptides isolated from the venom of the wolf spider Oxyopes kitabensis with cytolytic properties and positive insecticidal cooperativity with spider neurotoxins
RECORD: Rec_0266990 VERIFIED: YES
Provenance & Taxonomy
Oxyopes kitabensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Insecticidal
Staphylococcus aureus
6.2 μM
MIC
PaperOxyopinins, large amphipathic peptides isolated from the venom of the wolf spider Oxyopes kitabensis with cytolytic properties and positive insecticidal cooperativity with spider neurotoxins
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