‹ ›
MYP_156491
← PREVIOUS NEXT → BACK
Basic Information
EK0-3, HCoV-OC43-HR2P [Y4Q,Q13E,D14Y,N17K,R18K,Q20E,V25K,N27,Q28E,N32D,D35E]
Antiviral
Standard
36 amino acids
C196H317N43O64S
Standard
Sequence
SLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKEI
Physicochemical Analysis
4331.93 Da
4.36
-5.52
-5.76
-0.1534
-0.41
0.75
-0.04
28.07
119.17
0.0833
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1772.25
-9.98
59.0
60.0
156.0
304.0
3.0
37.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0140202 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
SARS-CoV
PMID30989115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30989115/
RECORD: Rec_0267112 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HCoV-NL63
PMID30989115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30989115/
RECORD: Rec_0330277 VERIFIED: YES
Provenance & Taxonomy
Human coronavirus OC43 [Virus]
HR2-derived fusion inhibitor
31631
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus
0.25 μM
IC50
PaperA pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike PMID30989115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30989115/
RECORD: Rec_0388870 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
MERS-CoV
PMID30989115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30989115/
RECORD: Rec_0426764 VERIFIED: YES
Provenance & Taxonomy
Human coronavirus OC43 [Virus]
HR2-derived fusion inhibitor
31631
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Human coronavirus OC43
0.49 μM
IC50
PaperA pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike PMID30989115 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30989115/
FIRST PREV 1 2
Showing 5 records on this page · Page 2 of 2