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MYP_156442
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Basic Information
Phakellistatin 16
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
9 amino acids
C48H70N12O15
Standard
Sequence
PFDSRAVTY
Physicochemical Analysis
1055.14 Da
6.26
-0.04
-0.10
-0.0046
-0.40
0.26
-0.04
77.37
43.33
0.2222
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
442.02
-4.32
17.0
15.0
30.0
75.0
3.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0057386 VERIFIED: YES
Provenance & Taxonomy
Phakellia fusca [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: BEL-7402
14.3 μM
IC50
PMID20345147 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20345147/
RECORD: Rec_0062291 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0123480 VERIFIED: YES
Provenance & Taxonomy
Phakellia fusca [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
P388
5.4 μM
IC50
PMID20345147 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20345147/
RECORD: Rec_0168236 VERIFIED: YES
Provenance & Taxonomy
Phakellia fusca [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID20345147 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20345147/
RECORD: Rec_0175345 VERIFIED: YES
Provenance & Taxonomy
Phakellia fusca [Animal]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Toxin Cytotoxic Anticancer
Human hepatoma BEL-7404 cell line, BEL-7404 cell line
0.01 μg/mL
ED50
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