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MYP_156424
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Basic Information
FLAKO6 AMD
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C102H186N26O20
Standard
Sequence
FALALKALKKLKKALKKAL
Physicochemical Analysis
2096.73 Da
10.78
6.75
6.54
0.3554
0.38
0.80
0.01
-12.87
149.47
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
769.26
-1.35
27.0
27.0
79.0
148.0
1.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0329277 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
8 μg/mL
MBC
PMID29679519 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29679519/
RECORD: Rec_0353293 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Human breast adenocarcinoma MCF-7
7 μM
EC50
PMID29679519 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29679519/
RECORD: Rec_0354212 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
FLAK
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
Antimicrobial Anticancer
PaperPatent US 2011/0319336 A1 Evidence URLhttps://patents.google.com/patent/US20110319336A1/en PatentUS 2011/0319336 A1
RECORD: Rec_0357788 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Human prostate adenocarcinoma PC-3
16 μg/mL
LD50
PMID29679519 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29679519/
RECORD: Rec_0361127 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
FLAK peptides
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
BMKC (skin cancer)
93 μg/mL
LD50
PaperPatent US_06875744_B2 | https://patents.google.com/?q=US_06875744_B2 PatentUS_06875744_B2
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