Peptide Database

Peptide NameBeta-defensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length160 amino acids

Chemical FormulaC747H1228N226O210S14

DescriptionStandard

        ELNPAAAGQRKVCARDSRTTQGKRREGWFIRISLRIATPPFRSPLLLCKCRPINTETLPALEASVSSASVSSASKEPLCLPRASRPGLPAAMRALSFLLLILCLVSSHLAPGAGFLSGLGQRSDHYMCARKGGTCNFSPCPLFTRLEGTCYGGKAKCCMR
    

Molecular Weight17184.04 Da

Isoelectric Point (pI)9.92

Net Charge (pH 7.0)14.91

Net Charge (pH 7.4) 14.45

Charge Density (pH 7.0) 0.0932

GRAVY Index-0.02

Hydrophobic Moment 0.63

Boman Index-0.01

Instability Index57.02

Aliphatic Index 81.25

Aromaticity 0.0563

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 9105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6924.79

LogP -78.48

H-bond Donors 258.0

H-bond Acceptors 241.0

Rotatable Bonds 558.0

Heavy Atoms 1197.0

Ring Count 25.0

Amide Bonds 165.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0019884 VERIFIED: NO

Provenance & Taxonomy

OrganismNeogale vison [Animal]

FamilyDefensin

Tax ID452646

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal