Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC371H610N94O106S9

DescriptionStandard

        MKLLLLVFTVTLLLAQVTPVMKCWGKSGRCRAMCKESEVYYILCNTEAKCCVDPKYVPVKPELANTNASLESASAV
    

Molecular Weight8371.96 Da

Isoelectric Point (pI)8.58

Net Charge (pH 7.0)2.45

Net Charge (pH 7.4) 2.12

Charge Density (pH 7.0) 0.0322

GRAVY Index0.34

Hydrophobic Moment 0.62

Boman Index0.12

Instability Index20.80

Aliphatic Index 100.00

Aromaticity 0.0658

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3191.54

LogP -26.77

H-bond Donors 116.0

H-bond Acceptors 118.0

Rotatable Bonds 275.0

Heavy Atoms 580.0

Ring Count 10.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0145237 VERIFIED: NO

Provenance & Taxonomy

OrganismSaimiri boliviensis boliviensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence