‹ ›
MYP_156393
← PREVIOUS NEXT → BACK
Basic Information
PSPHa
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
19 amino acids
C92H144N22O24
Standard
Sequence
FLSLIPAAISAVSALANHF
Physicochemical Analysis
1942.26 Da
6.74
-0.15
-0.41
-0.0080
1.50
0.39
0.57
12.64
144.21
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
710.79
-5.08
24.0
25.0
58.0
138.0
4.0
19.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0348044 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Horse erythrocytes
10 %
Hemolysis
PaperPubMed PMID: 28850103 PMID28850103 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28850103/
RECORD: Rec_0365923 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (NCTC10788) ( MIC= 8 microM), ( MBC= 16 microM), Escherichia coli (NCTC10418) ( MIC= >512microM), ( MBC= >512 microM), Candida albicans (NCYC1467) ( MIC= 32 microM), ( MBC= 32 microM), methicillin-resistant Staphylococcus aureus (NCTC12493) ( MIC= 64 microM), ( MBC= 128 microM), Enterococcus faecalis (NCTC12697) ( MIC= >512 microM), ( MBC= >512 microM), Pseudomonas aeruginosa (ATCC 27853) ( MIC= >512 microM), ( MBC= >512 microM), Klebsiella pneumoniae (ATCC 43816) ( MIC= >512 microM), ( MBC= >512 microM)
8 μM
MIC
PMID30774309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30774309/
RECORD: Rec_0391646 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-435S
28.48 μM
LD50
PaperPubMed PMID: 28850103 PMID28850103 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28850103/
RECORD: Rec_0397546 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis
512 μM
MIC
PMID30774309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30774309/
RECORD: Rec_0416385 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
317381
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Candida albicans NCYC 1467
131.89 μM
MIC
PaperDiscovery of Phylloseptins that Defense against Gram-Positive Bacteria and Inhibit the Proliferation of the Non-Small Cell Lung Cancer Cell Line, from the Skin Secretions of Phyllomedusa Frogs
FIRST PREV 1 ... 4 5 6 7 NEXT LAST
Showing 5 records · Page 6 of 7