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MYP_156393
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Basic Information
PSPHa
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
19 amino acids
C92H144N22O24
Standard
Sequence
FLSLIPAAISAVSALANHF
Physicochemical Analysis
1942.26 Da
6.74
-0.15
-0.41
-0.0080
1.50
0.39
0.57
12.64
144.21
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
710.79
-5.08
24.0
25.0
58.0
138.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0255782 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa hypochondrialis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Hemolytic
Candida albicans
2.07 μM
MIC
RECORD: Rec_0281942 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
methicillin-resistant Staphylococcus aureus
64 μM
MIC
PMID30774309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30774309/
RECORD: Rec_0286171 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
U-251MG
34.67 μM
LD50
PaperPubMed PMID: 28850103 PMID28850103 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28850103/
RECORD: Rec_0298631 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa hypochondrialis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Hemolytic Anti-Gram-positive
Staphylococcus aureus
4.14 μM
MIC
RECORD: Rec_0346460 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
8 μM
MIC
PMID30774309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30774309/
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